From USA Today:
United Airlines to add Denver-Panama City nonstop
This would have been great news for me in 2012, when I did a few flights between Colorado and Latin America. To Uruguay in my case, where I now live. I took United’s Star Alliance and Mileage Plus partner Copa on one of those flights, starting with a United connecting flight to a Copa Airlines international gateway. But had to fly to Washington Dulles (IAD) to connect to Copa.
From Panama, Copa Airlines has nonstop flights to many cities in South America, even to under-served Uruguay at our Montevideo International Airport (MVD). (Posted edited to expand information, add some links and images, after initial posting from WordPress’ inadequate mobile app.)